The basic panel of analyses at Biotest Facility consists of the common hematology parameters including three-part differential counts and the clinical chemistry parameters ALB, ALT, BUN, Ca, CHOL, CREA, GLOB, Phos, TBIL and TP. Besides this cost-effective selection, we offer extensions to the panel and we are always open to study specific requirements.
Clinical adverse symptoms revealed in the preclinical development, e.g. during administration to rodent research models, are valuable indicators of issues that must be addressed during the further development. We always document the relevant clinical observations, with measurements of hematology parameters and clinical chemistry, during one of the very first administrations of the test article to an animal research model.