The mice have entered Biotest Facility and we will take good care of them. They will have a health check every day and are caged in an enriched environment with hidings, bedding, nesting material, biding sticks and chow & water ad libitum. The cages are ventilated individually and the temperature will be between 20 and 24° C.
All animal studies are conducted according to Danish legislation and specific licenses issued by the Animal Experiments Inspectorate. Prospective and retrospective assessment of the inhumane intervention will be obtained individually for each animal and reported. The routine assessment and handling of the animals will be conducted by technicians which are continuously training the procedures and are under supervision of a dedicated veterinarian.
Biotest Facility is committed to continuous implementation of the principles of 3R, which stands for “Replacement”, “Reduction” and “Refinement”. Replacement entails that Biotest Facility is committed to replace experiments with conscious living organisms with insentient materials such as in vitro assays with cells in culture and isolated organs from animals. Reduction entails that Biotest Facility is committed to reduce the number of animals used in the experiments by careful planning and development of the analytical procedures to gain more scientific value from each animal. Refinement entails that Biotest Facility is committed to decrease the severity of inhumane procedures applied to the animals which must be used in an experiment.